WednesdayAugust 24, 2016

• 07:30 - 16:00

  IASLC School of Thoracic Oncology (Ticketed Event)*

  Location: Amsterdam, Riu Plaza Panama, Panama

  Chairs: Suresh Ramalingam, USA, Luis E. Raez, USA,

  
  *30 USD registration fee applies

  • Breakfast and Registration
  • Welcome and Introductions
  • Pre-Meeting Test
  • Pulmonary Medicine - Robert Keith, USA
  • Pathology - Fred Hirsch, USA & Marileila Varella-Garcia, USA
  • Thoracic Surgery - Harvey Pass, USA
  • Break
  • Radiation Oncology - Ana Botero, USA
  • Medical Oncology - Christian Rolfo, Belgium
  • Question and Answers
  • Biostatistics - Mary Redman, USA
  • Lunch
  • Workstation 1 (Pulmonary) - Robert Keith, USA
  • Workstation 2 (Pathology) - Ignacio Wistuba, USA
  • Workstation 3 (Thoracic Surgery) - Harvey Pass, USA
  • Break
  • Workstation 4 (Radiation Oncology) - Ana Botero, USA
  • Workstation 5 (Medical Oncology) - Luis E. Raez, USA
  • Post-Meeting Test
  • Wrap up and Adjourn

ThursdayAugust 25, 2016

• 10:00 - 11:45

  Patient Advocacy Session

  Location: Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Dr. Nise Yamaguchi, Brasil,

  • Chair Welcome, Nise Yamaguchi, Brasil
  • Tumor Molecular Profile: a new challenge Christian Rolfo, Belgium
  • Learning from patients: The story of...
  • Our body helping to cure cancer: Immunotherapy, Roberto Lopez, Panama
  • Celebrating the survivors: The story of...
  • Is easy to get new drugs in Latin America?, Nise Yamaguchi, Brasil
  • Open discussion Moderated by: Christian Rolfo, Belgium
  • Closing Remarks, Nise Yamaguchi, Brasil

• 12:00 - 13:00

  Opening Ceremony

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Roberto I. Lopez, Panama, Edgardo S. Santos, USA,

  • Welcome and Introduction to LALCA 2016 - Edgardo S. Santos, USA
  • The Future of Lung Cancer Management in Panama - Roberto I. Lopez, Panama
  • Welcome from IASLC CEO - Fred R. Hirsch, IASLC CEO, USA
  • Welcome from President of Republic of Panama
  • Welcome from the Panamanian Minister of Health

• 13:00 - 14:00

  Cancer Control Program and Tobacco Forum

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Nise Yamaguchi, Brazil, Erick Arauz, Panama,

  • Early Detection in Heavy Smoker - Ricardo Sales do Santos, Brazil
  • Importance of Smoking Cessation in the Treatment of Lung Cancer Patient - Carolyn Dresler, USA
  • Tobacco Control in Youth - Nise Yamaguchi, Brazil

• 14:15 - 15:15

  Industry Symposium Supported by Varian Medical System

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: , ,

  • The Role of Salvage SBRT in Recurrent Lung Cancer after Previous Radiotherapy

• 14:15 - 15:15

  Industry Symposium Supported By Caris

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: , ,

  • Multiplatform Tumor Profiling in Lung Cancer

• 15:30 - 16:30

  Lung Cancer Screening

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Ignacio Gil-Bazo, Spain, Luis Herrera, USA,

  • Lung Cancer Computer Tomography Screening - Claudia I. Henschke, USA
  • Lung Cancer Screening: Impact in Survival and Economics - Luis Corrales-Rodriguez, Costa Rica
  • Lung Cancer Screening in America: Challenges and Progress - Carlos Barrios, Brazil

• 16:45 - 17:45

  Young Investigators Session

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Maria Lim, Panama, Belisario Arango, USA,

  • How to Write a Manuscript and a Research Grant? - Gilberto Lopes, Brazil
  • How to Incorporate Research in Panama and Latin America? - Roberto I. Lopez, Panama
  • The Role of Medical School to Promote Basic and Clinical Research: Obstacles, Resources and Policies - Enrique Mendoza, Panama

• 16:45 - 17:45

  Diagnostic Imaging Innovations

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Luis Leonardo Rojas, Colombia, Hector Tapia, Panama,

  • PET CT Scan as a Tool for Lung Cancer Management: Utility - Yariela Herrera Malo, Panama
  • EBUS and Navigation System to Yield a Diagnosis - Jonathan Waxman, USA
  • Stereotactic Body Radiotherapy in NSCLC with Oligometastic Disease - Ana Botero, USA
  • Role of Interventional Radiology in the Modern Era of Lung Cancer - Ligia Cardona, Dominican Republic

• 18:00 - 19:00

  Industry Symposium Supported by MSD

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: , ,

  • Immuno-Oncology: A Renaissance in the Treatment of NSCLC

• 18:00 - 19:00

  Industry Symposium Supported by AstraZeneca

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: , ,

  • Advances in Therapy of EGFR-mutated Lung Cancer

• 19:00 - 20:30

  Welcome Reception

  Location: Panama 3 & 4, Riu Plaza Panama, Panama

  Chairs: Dr. Roberto I. Lopez , Dr. Edgardo S. Santos,

FridayAugust 26, 2016

• 08:00 - 09:15

  Presidential Symposium

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Roberto I. Lopez, Panama, Edgardo S. Santos, USA, David Carbone, USA

  Discussant: Roy Herbst, USA
  

  • O.01 - Acquired Resistance to EGFR-TKIs in EGFR-Mutant Lung Adenocarcinoma Among Hispanics (Rbiop-CLICaP) - Oscar Arrieta, MX
  • O.02 - Plasma next Generation Sequencing of over 5,000 Advanced Non-Small Cell Lung Cancer Patients with Clinical Correlations - David Gandara, USA
  • O.03 - Cost Effectiveness of Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer Relative to PD-L1 Expression - Gilberto Lopes, BR
  • O.04 - Profiling of MET-Amplified Non-Small Cell Lung Cancer (NSCLC), Correlation to cMET Protein Expression/MET Exon 14 Skipping - David Arguello, USA

• 09:30 - 10:30

  Innovative Clinical Trial Designs for NSCLC

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Carlos Vallejos, Peru, Robert Pirker, Austria,

  • Bringing Opportunities in Clinical Research for Latin America - Christian Caglevic, Chile
  • Master Protocol - David Gandara, USA
  • Lung MAP - Roy Herbst, USA
  • Bringing Research to the Patient: Remote Consenting for a Novel Trial- Genomics of Young Lung Cancer - Barbara Gitlitz, USA

• 10:30 - 11:00

  Networking Break and Poster Viewing

  Location: Panama 3 & 4 (Level 4), Riu Plaza Panama, Panama

  Chairs: , ,

• 11:00 - 12:00

  Lung Cancer Pathology in the Era of Targeted Therapy

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Marileila Varella-Garcia, USA, Ruth Vergara, Panama,

  • The Importance of Histologic Diagnosis in Lung Cancer: Clinical Implications - Robert Pirker, Austria
  • Tissue Quality Control for Molecular Testing - Ignacio I. Wistuba, USA
  • Gene expression Profile for Carcinoma of Unknown Primary - Carlos Barrios, Brazil
  • Questions and Answers

• 11:00 - 12:00

  Diagnostic and Staging Issues in the Contemporary Pulmonary Medicine

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Francisco Tarrazzi, USA, Carlomagno Castillero, Panama,

  • Assessment of the Pulmonary Nodule - Mark Block, USA
  • Potential and Limitations of EBUS for Diagnosis and Staging - Francisco Tarrazzi, USA
  • Optimization of Bronchoscopic Samples in the Era of Molecular Pathology - Johan Vansteenkiste, Belgium
  • Roadmap for Liquid Biopsy in Lung Cancer - Christian Rolfo, Belgium

• 12:15 - 13:15

  Molecular Markers in Lung Cancer

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Jaime De La Garza, Mexico, Bruno Bastos, USA,

  • Molecular Markers in Lung Adenocarcinomas - Marileila Varella-Garcia, USA
  • Molecular Markers in Squamous Cell Carcinoma - Luis E. Raez, USA
  • Molecular Diagnosis Guidelines Recommended Internationally - Fred R. Hirsch, USA
  • Molecular Testing in Lung Cancer: Efforts and Perspectives in Latin America - Tatiana Vidaurre, Peru

• 12:15 - 13:15

  New Developments in Surgery

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Mark Block, USA, Rafael Andrade, Panama,

  • Invasive Mediastinal Staging: Mediastinoscopy, EBUS and EUS - Jonathan Waxman, USA
  • VATS, Robot-Assisted or Thoracotomy for Lung Cancer Surgery - Mark Block, USA
  • Sublobar Resection for Stage I NSCLC - Harvey Pass, USA
  • Endosonography and Navigation System to Secure Tissue Diagnosis - Johan Vansteenkiste, Belgium

• 13:30 - 14:30

  Industry Symposium Supported by Boehringer Ingelheim

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: , ,

  • Treatment Updates in NSCLC: Translating Evidence into Clinical Practice

• 14:45 - 16:00

  Adjuvant Therapy in the Molecular Era

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Barbara Gilitz, USA, Clarissa Mathias, Brazil,

  • Adjuvant Chemotherapy for NSCLC: Where Are We Now? - Norma Pilnik, Argentina
  • Role of Targeted Agents in the Adjuvant Setting - Raja Mudad, USA
  • Is There a Role for Immunotherapy in Lung Cancer Adjuvant Setting? - Luis Paz-Ares, Spain
  • Prognostic and Predictive Makers for Adjuvant Therapy NSCLC - Gilberto Lopes, Brazil
  • Question and Answer Period

• 16:00 - 16:30

  Networking Break and Poster Viewing

  Location: Panama 3 & 4 (Level 4), Riu Plaza Panama, Panama

  Chairs: , ,

• 16:30 - 17:30

  Stage IIIA/B Non-Small Cell Lung Cancer

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Jorge Gomez, USA, Carlos Barrios, Brazil,

  • Optimal Radiation Dose and Schedule - Puneeth Iyengar, USA
  • Optimal Combined Modality Therapy for LA-NSCLC - Alberto Chiappori, USA
  • Is There a Role of Neoadjuvant Therapy for N2 Disease - Harvey Pass, USA
  • Integration of Molecular Imaging and Agents in LA-NSCLC - Johan Vansteenkiste, Belgium

• 16:30 - 17:30

  Squamous Cell Carcinoma

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Jhanelle Gray, USA, Alejandro Crissmatt, Panama,

  • Biological insights of Squamous Cell Carcinoma—Novel Targets - Suresh Ramalingam, USA
  • Maintenance Therapy in Squamous Cell Carcinoma - Luis Leonardo Rojas Puentes, Colombia
  • Checkpoint Inhibitors and Vaccine in Squamous Cell Carcinoma - Glenwood Goss, Canada
  • Emerging Approaches to the Therapy of Advanced Squamous Cell Lung Cancer - David Gandara, USA

• 17:45 - 18:45

  Industry Symposium Supported by Pfizer

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: , ,

  • ROS-1: How to Incorporate New Markers into Oncogene Driven Treatments

• 19:00 - 20:00

  Industry Symposium Supported Guardant Health

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: , ,

  • Clinical Utility of Liquid Biopsies to Determine NCCN Mutation Targets in NSCLC

• 20:15 - 23:00

  Faculty Dinner (By Invitation Only)

  Location: , ,

  Chairs: , ,

SaturdayAugust 27, 2016

• 08:00 - 09:15

  Poster Discussion Session - Topic 1

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Roberto I. Lopez, Panama, Edgardo S. Santos, USA,

  Discussants:
  Nise Yamaguchi, Brazil
  Mercedes Liliana Dalurzo, Argentina

  • PD1. 01 - LCSS as a Marker of Treatment Benefit with Nivolumab vs Docetaxel in Pts with Advanced Non-Squamous NSCLC from CheckMate 057 - Clarissa Mathias, BR
  • PD1. 02 - The Role of PD-L1 Expression as a Predictive Biomarker in Advanced NSCLC: An Update of a Network Meta-Analysis - Gilberto Lopes, BR
  • PD1. 03 - EGFR Mutation Testing Patterns and Results in Brazil and the Need for Greater Public Health Awareness of Molecular Testing - Gilberto Lopes, BR
  • PD1. 04 - Infrequent Staining Patterns in ALK Immunohistochemistry: Correlation with Fish Analysis - Paola De La Iglesia, AR
  • PD1. 05 - The Genomics of Young Emergent Lung Cancer - Barbara Gitlitz, US
  • PD1.06PD01.06 - Pembrolizumab vs Docetaxel for Previously Treated NSCLC (KEYNOTE-010): Archival vs New Tumor Samples for PD-L1 Assessment, Roy Herbst, USA

• 08:00 - 09:15

  Poster Discussion Session - Topic 2

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Luis E. Raez, USA, David Carbone, USA,

  Discussants:
  Antoinette Wozniak, USA
  Clarissa Mathias, Brazil

  • PD2. 01 - Lung Cancer Chromosomal Aberrations and Gene Expression Profiles of Hispanics Living in the US or Latin America Are Similar - Luis Raez, USA
  • PD2. 02 - Phase I/II Trial of X-396, a Novel ALK Inhibitor, in Patients with ALK+ NSCLC - Ticiana Leal, USA
  • PD2. 04 - Pem/CBP/Bev Followed by Maintenance Pem/Bev in Hispanic Patients with NSCLC: Outcomes According to TS, ERCC1 and VEGF - Leonardo Rojas, CO
  • PD2. 05 - Radiosurgery, a New Paradigm in Metastatic Non-Small Cell Lung Cancer (NSCLC) to the Brain: An Update - Beatriz Amendola, USA
  • PD2. 06 - Bayesian Network Meta-Comparison of Maintenance Treatments for Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients - Gilberto Lopes, BR

• 09:30 - 10:30

  Management of Advanced Stage Non Squamous-NSCLC

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Luis Paz-Ares, Spain, Miguel Villalona, USA,

  • Front Line Therapy for EGFR/ALK/ROS-1 Genomic Aberrations - Luis Paz-Ares, Spain
  • How to Deal with ALK Resistance- How Far to Go? - Christian Rolfo, Belgium
  • Selecting Patients for Maintenance Therapy - Giorgio Scagliotti, Italy
  • Molecular Targeted Therapy for Brain Metastases and Leptomeningeal Disease - Jorge Gomez, USA

• 09:30 - 10:30

  Immunotherapy in Non-Small Cell Lung Cancer

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Ana Oton, USA, Eduardo Richardet, Argentina,

  • Immunotherapy: Making it in a Simple Language - Ada Blidner, Argentina
  • Predictive Assays for Immunotherapy - Fred Hirsch, USA
  • Clinical Trials with Anti-PD-1 - Luis E. Raez, USA
  • Clinical Trials with Anti-PDL-1 Inhibitors - Clarissa Mathias, Brazil
  • Other Immunotherapy Pathways - CTL4 and Others - David Carbone, USA
  • Questions and Answers

• 10:30 - 11:00

  Networking Break and Poster Viewing

  Location: Panama 3 & 4 (Level 4), Riu Plaza Panama, Panama

  Chairs: , ,

• 11:00 - 12:30

  Round Table Discussions

  Location: Berlin 1 & 2 , Riu Plaza Panama, Panama

  Chairs: Eduardo Richardet, Argentina, Edgardo S. Santos, USA,

  
  Novel Approaches in Surgery: Robotic Surgery, VATS, Navigation System - Luis Herrera, USA & Harvey Pass, USA
  
  Palliative Care in Lung Cancer - Erick Arauz, Panama & Luis Mas Lopez, Peru
  Commentator: Luis Ubillos, Uruguay
  
  Treatment of Wild Type Lung Cancer Tumours First and Second Line: TBA
  Commentator: Diego Kaen, Argentina
  
  Therapy of Tumours Carrying EGFR Mutations or ALK Translocations - Jorge Rios, USA & Maria Pietanza, USA
  Commentator: Martin E. Richardet, Argentina
  
  How to Study Molecular Biology and Tumour Markers - Ignacio Wistuba, USA & Ruth Vergara, Panama
  
  Radiation Therapy in Lung Cancer - Michael Kasper, USA & Ignacio Castellon, USA
  Commentator: Gaspar Perez Jimenez, Panama
  
  New Molecules and Therapies for Lung Cancer - Suresh Ramalingam, USA & Luis Leonardo Rojas Puentes, Colombia Commentator: Martin Dietrich, USA
  
  Diagnosis and Staging in Lung Cancer - Marileila Varella-Garcia, USA & Cesar Perez, USA
  Commentator: Mauricio Cuello, Uruguay
  
  Locally Advanced Non-Small Cell Lung Cancer - Giorgio Scagliotti, Italy & Jhanelle Gray, USA
  Commentator: Luis Corrales-Rodriguez, Costa Rica
  
  Therapy of EGFR/ALK Resistant Lung Cancer Tumours - Bruno Bastos, USA & Roy Herbst, USA
  Commentator: Claudio Martin, Argentina
  
  Management of Toxicities from Immunotherapies in Lung Cancer - Luis Paz-Ares, Spain & Christian Rolfo, Belgium Commentator: Belisario Arango, USA
  
  Adjuvant Therapy in Non-Small Cell Lung Cancer - Raja Mudad, USA & Oscar Arrieta, Mexico Commentator: Norma Pilnik, Argentina
  
  Management of Limited and Extensive Small Cell Lung Cancer - Glenwood Goss, Canada & Sai-Hong Ou, USA
  Commentator: Edgardo Santos, USA
  
  

• 12:45 - 13:45

  Small Cell Lung Cancer & Neuroendocrine Tumor (NET)

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Oscar Arrieta, Mexico, Cesar Perez, USA,

  • Small Cell Cancer Biology: Are There New Targets? - Maria Pietanza, USA
  • Systemic Chemotherapy for SCLC - Nise Yamaguchi, Brazil
  • Success and Challenges of Radiation Therapy for SCLC - Ignacio Castellon, USA
  • Management of Well-Differentiated NET - Aurelio Castrellon, USA

• 12:45 - 13:45

  Advanced Radiation Technology

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Puneeth Iyengar, USA, Ana Botero, USA,

  • Radiation Oncology Challenges in Latin America - Ignacio Castellon, USA
  • Role of SBRT in Early Stage NSCLC - Puneeth Iyengar, USA
  • Role of SBRT in Advanced NSCLC - Michael Kasper, USA
  • Role of Proton in Lung Cancer - Ana Botero, USA

• 14:00 - 15:00

  Independent Industry Symposium

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: , ,

  • Individualizing the Treatment of Advanced NSCLC (A Springer Healthcare IME independent symposium made possible thanks to independent educational sponsorship from Eli Lilly and Company)

• 15:15 - 16:15

  Novel Therapies Targeting Lung Cancer Pathways

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Paul Bunn, USA, ,

  • RET/BRAF - Antoinette Wozniak, USA
  • MET and MET Exon 14 Skipping - Paul Bunn, USA
  • Repair Inhibitors - Miguel Villalona, USA
  • NF-1 - David Carbone, USA
  • ROS-1 - Ignacio Gil-Bazo, Spain
  • Questions and Answer Period

• 15:15 - 16:15

  Mesothelioma, Thymoma, and Thymic Carcinoma

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Jorge Rios, USA, Sai-Hong Ou, USA,

  • VATS and Robotic Surgery in Mesothelioma - Francisco Tarrazzi, USA
  • Biological insights and Novel Therapy for Malignant Mesothelioma - Sai-Hong Ou, USA
  • Current Standard of Care for the Treatment of Thymoma: What's New? - Luis Corrales-Rodriguez, Costa Rica
  • Emerging Biology and Therapeutics in Thymic Carcinoma - Jorge Gomez, USA

• 16:15 - 16:45

  Networking Break and Poster Viewing

  Location: Panama 3 & 4 (Level 4), Riu Plaza Panama, Panama

  Chairs: , ,

• 16:45 - 17:45

  Epidermal Growth Factor Receptor (EGFR) Mutation as Targeted Therapy

  Location: Panama 1, Riu Plaza Panama, Panama

  Chairs: Sai-Hong Ou, USA, Manuel Magallanes Maciel, Mexico,

  • Actual Status of First and Second Generation EGFR TKIs in the Treatment of NSCLC - Fred R. Hirsch, USA
  • Targeting T790M in Lung Cancer: AZD9291 and Rociletinib - Suresh Ramalingam, USA
  • New Insights of EGFR Inhibition: EGF816, ASP8273, and AUY922 - Paul Bunn, USA
  • EGFR TKIs with Central Nervous System Penetration for Management of Lung Cancers - Sai-Hong Ou, USA

• 16:45 - 17:45

  ALK/EML4 Translocation as Targeted Therapy

  Location: Panama 2, Riu Plaza Panama, Panama

  Chairs: Alfredo Aguilar, Peru, Cesar Perez, USA,

  • Crizotinib and Ceritinib, the Approved ALK Inhibitors: Where Are We Now? - Ana Oton, USA
  • Novel Molecular Mechanisms of Resistance to ALK Inhibition - Clarissa Mathias, Brazil
  • ALK inhibitors with Central Nervous System Penetration for Management of Lung Cancers - Jhanelle Gray, USA
  • ALK Inhibitors in Combination with Other Targeted Therapies and Radiotherapy in Patients with ALK+ NSCLC - Luis Ubillos, Uruguay

• 18:00 - 18:45

  Closing Ceremony

  Location: Panama 1 , Riu Plaza Panama, Panama

  Chairs: Roberto Lopez, Panama, Edgardo S. Santos, USA,

  • Summary of Top Rated Abstracts
  • Award Presentations - Roberto Lopez, Panama
  • Closing Remarks - Edgardo S. Santos, USA & Fred R. Hirsch, USA

SundayAugust 28, 2016